Primate Genetics and Genomics Data
On this page, are links to genetics and genomics data resulting from the research activities of scientists at the SNPRC and elsewhere using SNPRC animal resources. The SNPRC makes these data available to inform and serve researchers in all areas of biomedicine and biology.
While human biology and biomedicine have benefited greatly from research using well-known, smaller and relatively easy to manipulate animal models, genetic studies of complex traits in nonhuman primates are of direct value given their close phylogenetic, anatomical, and physiological relationships to our own species. Genes discovered in humans can be investigated further in nonhuman primates and, conversely, genes discovered in nonhuman primates are very likely to be found in humans as well.
At this time, the majority of data available at this site are derived from studies of pedigreed populations of baboons (Papio hamadryas ssp.) and rhesus macaques (Macaca mulatta). These data include information characterizing the whole genome, genetic linkage maps for both species and the results of statistical, biochemical and molecular genetics research using these maps. Already, both have been used successfully to localize QTLs influencing variation in risk factors for common diseases of complex etiology in humans – e.g., cardiovascular disease, diabetes, obesity, and osteoporosis; as well as QTLs affecting normal variation in structure and function at multiple levels of biological organization. In addition to results of whole-genome transcriptional profiling in baboon lymphocytes, we are accumulating data from whole genome and targeted sequencing efforts, candidate gene association analyses, and gene expression studies in various tissues and organ systems.
